General anaesthesia was first recognized during a public surgical demonstration on October 16, 1846 by William Morton, a dentist that successfully used the vapours of sulphuric ether in a patient, for the removal of a …

During general anaesthesia the anesthesiologist’s goals are to render the patient pain free and amnesic, to preserve the vital functions during the operation and to offer to the surgeon a quiet relaxed field.
Modern anaesthesia achieves …

PHARMACOLOGIC PRINCIPLES
An agent for regional anesthesia produces a nondepolarizing block that takes effect at the surface membrane of excitable tissue cells (smooth muscle of blood vessels, myocardium and nerve fibers).
The site of action of such …

Local anaesthesia lay -in a reversible block, of the tranmission of peripheral nerve impulses, that is performed by using local anesthetics.
The mode of action of local anaesthetics is by blocking membrane depolarisation in all excitable …